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CD13 抗体 (Biotin)

This anti-CD13 antibody is a Human Chimeric antibody detecting CD13 in FACS. Suitable for 人.
产品编号 ABIN7608046
发货至: 中国

Quick Overview for CD13 抗体 (Biotin) (ABIN7608046)

抗原

See all CD13 (ANPEP) 抗体
CD13 (ANPEP) (Alanyl (Membrane) Aminopeptidase (ANPEP))

适用

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宿主

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Human, 兔

克隆类型

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Chimeric

标记

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This CD13 antibody is conjugated to Biotin

应用范围

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Flow Cytometry (FACS)

克隆位点

26H2
  • 原理

    Biotinylated Anti-ANPEP antibody(26H2), IgG1 Chimeric mAb

    纯化方法

    Purified from cell culture supernatant by affinity chromatography

    亚型

    IgG1
  • 应用备注

    Flow Cyt 1/100

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

    储存条件

    -20 °C,-80 °C

    储存方法

    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

    有效期

    12 months
  • 抗原

    CD13 (ANPEP) (Alanyl (Membrane) Aminopeptidase (ANPEP))

    别名

    ANPEP

    背景

    Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily. Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical. The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS. This membrane-bound zinc metalloprotease is known to serve as a receptor for the HCoV-229E alphacoronavirus as well as other non-human coronaviruses. This gene has also been shown to promote angiogenesis, tumor growth, and metastasis and defects in this gene are associated with various types of leukemia and lymphoma. [provided by RefSeq, Apr 2020]

    UniProt

    P15144

    途径

    Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones
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